Description

6-Fluoro-2-Chromanone is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom is strategically introduced to modulate biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where fluorination enhances efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for fluorinated organic materials, including liquid crystals and advanced polymers.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including novel fluorination and cyclization reactions.

Basic Information

Product Name	6-Fluoro-2-Chromanone
CAS No.	75487-95-5
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-one; 6-Fluoro-2H-1-benzopyran-2-one, 3,4-dihydro-; 2-Chromanone, 6-fluoro-; 6-Fluorochroman-2-one; 6-Fluoro-3,4-dihydro-2H-chromen-2-one
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Chromanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.