Description

6-Fluoro-2H-Chromen-2-One is a fluorinated derivative of coumarin, a privileged scaffold in medicinal chemistry and organic synthesis. This compound matters as a versatile and high-value building block for developing novel pharmaceutical intermediates and functional materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced material science industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Fluorescent Probe Synthesis: Acts as a core structure for creating advanced fluorescent dyes and molecular probes used in bioimaging and diagnostics.
• Organic Light-Emitting Diodes (OLEDs): Investigated as an electron-transport or emissive layer component in the fabrication of OLED devices.
• Polymer Chemistry: Incorporated into polymer backbones to impart specific optical or electronic properties to advanced materials.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry to study fluorination effects and reaction mechanisms.

Basic Information

Product Name	6-Fluoro-2H-Chromen-2-One
CAS No.	75487-82-0
Molecular Formula	C9H5FO2
Molecular Weight	164.13 g/mol
Synonyms	6-Fluorocoumarin; 6-Fluoro-2H-1-Benzopyran-2-One; 6-Fluoro-1-Benzopyran-2-One; 6-Fluorochromen-2-one; 2H-Chromen-2-one, 6-fluoro-; 6-Fluoro-2-chromenone; 6-Fluoro-2-oxo-2H-chromene
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2H-Chromen-2-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.