Description

(1S,4S)-5α-Ethenyl-1-Azabicyclo[2.2.2]Octane-2-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and bicyclic quinuclidine-like core structure. This compound matters for its critical role as a sophisticated building block in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those targeting the nervous system.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides with specific stereochemical requirements.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis.
• Academic & Industrial Research: A valuable compound for methodological development in organic synthesis and medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of high-value, complex fragrance and flavor ingredients.

Basic Information

Product Name	(1S,4S)-5α-Ethenyl-1-Azabicyclo[2.2.2]Octane-2-Carbaldehyde
CAS No.	75364-48-6
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(1S,4S)-5-Vinylquinuclidine-2-carboxaldehyde; (1S,4S)-5-Vinyl-2-quinuclidinecarboxaldehyde; (1S,4S)-5-Ethenyl-2-quinuclidinecarbaldehyde; (1S,4S)-5-Vinyl-1-azabicyclo[2.2.2]octane-2-carbaldehyde; 5-Vinylquinuclidine-2-carboxaldehyde; 5-Ethenylquinuclidine-2-carbaldehyde; (1S,4S)-5-Vinyl-2-formylquinuclidine; (1S,4S)-5-Vinylquinuclidine-2-aldehyde
EINECS	Contact for details

Quality Control

Our (1S,4S)-5α-Ethenyl-1-Azabicyclo[2.2.2]Octane-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.