Description

3-(4-Chloro-2-Methylphenyl)-5-(3-Methoxyphenyl)-1H-1,2,4-Triazole is a high-purity, functionalized 1,2,4-triazole derivative, a versatile heterocyclic scaffold of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the triazole core is prized for its bioactivity and stability. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anti-infectives.
• Agrochemical Research: Used as a core structure for developing new generation fungicides, herbicides, and plant growth regulators, leveraging the bioactivity of the 1,2,4-triazole moiety.
• Material Science: Acts as a monomer or cross-linking agent in the production of advanced polymers, coatings, and liquid crystals with enhanced thermal and chemical stability.
• Chemical Synthesis: Functions as a versatile ligand in organometallic chemistry and catalysis, or as a building block for more complex heterocyclic systems.
• Analytical Standard: Supplied as a certified reference material (CRM) for quality control and analytical method development in regulatory and research laboratories.

Basic Information

Product Name	3-(4-Chloro-2-Methylphenyl)-5-(3-Methoxyphenyl)-1H-1,2,4-Triazole
CAS No.	75318-76-2
Molecular Formula	C16H14ClN3O
Molecular Weight	299.75 g/mol
Synonyms	3-(4-Chloro-2-methylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole; 1H-1,2,4-Triazole, 3-(4-chloro-2-methylphenyl)-5-(3-methoxyphenyl)-; 5-(3-Methoxyphenyl)-3-(4-chloro-2-methylphenyl)-1,2,4-triazole; 3-(4-Chloro-o-tolyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole; 75318-76-2; 4-Chloro-2-methylphenyl-3-methoxyphenyl-1,2,4-triazole derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-2-Methylphenyl)-5-(3-Methoxyphenyl)-1H-1,2,4-Triazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.