Description

Ethanone, 1-(2-Benzofuranyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a benzofuran scaffold, a structure of significant interest in advanced organic synthesis. This compound serves as a key fluorinated building block for the development of novel molecules with tailored properties. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries seeking to incorporate the trifluoromethyl group into heterocyclic systems to modulate bioactivity, metabolic stability, and physicochemical parameters.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry & Catalysis: Employed as a substrate or ligand in organometallic chemistry and catalytic reactions to study fluorine-specific effects.
• Chemical Biology Probe: Useful for creating activity-based probes or inhibitors to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethanone, 1-(2-Benzofuranyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	75277-96-2
Molecular Formula	C10H5F3O2
Molecular Weight	214.14 g/mol
Synonyms	1-(Benzofuran-2-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-benzofuranyl)ethanone; 2-(Trifluoroacetyl)benzofuran; 2-Benzofuranyl trifluoromethyl ketone; 1-(2-Benzofuranyl)-2,2,2-trifluoroethanone; Trifluoroacetylbenzofuran; 2-Trifluoroacetylbenzofuran
EINECS	Contact for details

Quality Control

Our high-purity Ethanone, 1-(2-Benzofuranyl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.