Description

1,1,1-Trimethoxy-2-Chloroethane is a versatile organochlorine compound with a unique structure combining alkoxy and chloro functionalities. This chemical serves as a valuable intermediate and reagent in advanced organic synthesis, enabling the introduction of protected aldehyde or acetal groups. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Acts as a versatile reagent for acetal formation and as a protected aldehyde equivalent in multi-step synthetic routes.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other high-value specialty chemicals.
• Cross-Coupling Reactions: Potential substrate in metal-catalyzed cross-coupling reactions to construct complex carbon frameworks.
• Polymer Chemistry: Can be utilized as a monomer or modifying agent in the synthesis of specialized polymers and resins.

Basic Information

Product Name	1,1,1-Trimethoxy-2-Chloroethane
CAS No.	74974-54-2
Molecular Formula	C5H11ClO3
Molecular Weight	154.59 g/mol
Synonyms	2-Chloro-1,1,1-trimethoxyethane; Chloroacetaldehyde Dimethyl Acetal; (Chloromethyl) Dimethyl Acetal; 1-Chloro-2,2,2-trimethoxyethane; α-Chloroacetaldehyde Dimethyl Acetal; Acetaldehyde, chloro-, dimethyl acetal; Trimethyl Orthochloroacetate (related compound); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 1,1,1-Trimethoxy-2-Chloroethane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.