Description

1-Chloro-8-Iodooctane is a high-purity bifunctional halogenated alkane, a versatile building block in advanced organic synthesis. Its distinct structure, featuring terminal chloro and iodo groups separated by a flexible eight-carbon chain, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel compounds through reliable cross-coupling and nucleophilic substitution reactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating long-chain alkyl linkers or prodrugs.
• Agrochemical Synthesis: Used in the production of specialized pesticides and herbicides where specific halogenated alkane chains are required for biological activity.
• Liquid Crystal & OLED Materials: Acts as a building block for synthesizing mesogenic units and charge-transport materials in display and lighting technologies.
• Polymer & Dendrimer Chemistry: Employed in step-growth polymerization and as a functional initiator or terminating agent for creating polymers with precise end-group functionality.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Heck, Suzuki, Sonogashira) where the iodo group offers superior reactivity compared to other halogens.
• Surface Modification & Nanomaterial Functionalization: Used to attach organic chains to surfaces or nanoparticles, altering their hydrophobicity, reactivity, or compatibility.

Basic Information

Product Name	1-Chloro-8-Iodooctane
CAS No.	74962-58-6
Molecular Formula	C8H16ClI
Molecular Weight	274.57 g/mol
Synonyms	8-Chloro-1-iodooctane; Octane, 1-chloro-8-iodo-; 1-Iodo-8-chlorooctane; 8-Iodo-1-chlorooctane; Chloroiodooctane; Iodochlorooctane; ω-Chloro-ω'-iodooctane; 1-Chlorooctyl Iodide
EINECS	Contact for details

Quality Control

Our 1-Chloro-8-Iodooctane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C to maximize shelf-life stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.