Description

α-Bromo-4-Amino-3-Nitroacetophenone is a specialized halogenated aromatic ketone derivative, serving as a critical high-purity building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, amino, and nitro functional groups on an acetophenone core, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those with nitro-aromatic or halogen-substituted pharmacophores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, leveraging its reactive halogen and nitro groups.
• Organic Synthesis Building Block: Serves as a versatile starting material for heterocyclic chemistry, facilitating the construction of pyrroles, indoles, and other nitrogen-containing rings.
• Dye and Pigment Intermediate: Employed in the production of specialized azo dyes and colorants due to its amino and nitro functional groups.
• Material Science Research: Utilized in academic and industrial R&D for creating novel organic materials and ligands for metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for carbon-nitrogen and carbon-carbon bond formation.

Basic Information

Product Name	α-Bromo-4-Amino-3-Nitroacetophenone
CAS No.	74902-59-3
Molecular Formula	C8H7BrN2O3
Molecular Weight	259.06 g/mol
Synonyms	2-Bromo-1-(4-amino-3-nitrophenyl)ethanone; 1-(4-Amino-3-nitrophenyl)-2-bromoethanone; 4-Amino-3-nitro-ω-bromoacetophenone; ω-Bromo-4-amino-3-nitroacetophenone; Bromo(4-amino-3-nitrophenyl)methyl ketone; α-Bromo-4-amino-3-nitroacetophenone; 2-Bromo-1-(4-amino-3-nitrophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our α-Bromo-4-Amino-3-Nitroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and reactivity with strong acids and organic solvents, keep the container sealed and separate from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.