Description

α-(Dimethylsilyl)-N,n-Dimethylmethanamine is a specialized organosilicon compound featuring a reactive silyl group linked to a tertiary amine. This unique bifunctional structure makes it a valuable silylating agent and versatile intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the protection of functional groups and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing moieties or protecting amine groups during multi-step synthesis.
• Agrochemical Synthesis: Serves as a key building block in the production of novel pesticides, herbicides, and plant growth regulators that incorporate silicon for enhanced efficacy or stability.
• Silylating Agent: Employed to introduce the (dimethylsilyl)methyl group onto various nucleophiles, modifying the properties of target molecules for material science applications.
• Surface Modification: Acts as a coupling agent or precursor for modifying the surface properties of silica, metals, or polymers to improve adhesion, hydrophobicity, or biocompatibility.
• Catalyst Ligand Precursor: Utilized in the preparation of novel ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Research & Development: A critical reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating silicon-based chemical libraries.

Basic Information

Product Name	α-(Dimethylsilyl)-N,n-Dimethylmethanamine
CAS No.	74897-04-4
Molecular Formula	C6H17NSi
Molecular Weight	131.29 g/mol
Synonyms	N,N-Dimethyl-1-(dimethylsilyl)methanamine; (Dimethylsilyl)methyl dimethylamine; (Dimethylaminomethyl)dimethylsilane; N,N-Dimethyl[(dimethylsilyl)methyl]amine; DMADMS; 1-(Dimethylsilyl)-N,N-dimethylmethanamine; N-[(Dimethylsilyl)methyl]-N-methylmethanamine
EINECS	Contact for details

Quality Control

Our production of α-(Dimethylsilyl)-N,n-Dimethylmethanamine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques including GC, NMR, and Karl Fischer titration. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.