Description

Ethanone, 2,2,2-Trifluoro-1-[1-(1-Methylethyl)-1H-Pyrrol-3-Yl]- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a substituted pyrrole ring, offering unique reactivity and electronic properties. This compound is valued as a versatile building block in advanced organic synthesis, particularly for introducing the trifluoroacetyl group into complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a precursor for functional polymers and advanced organic electronic materials due to its unique electronic properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Fluorine Chemistry Studies: An important reagent for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[1-(1-Methylethyl)-1H-Pyrrol-3-Yl]- (9Ci)
CAS No.	74889-34-2
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	1-(1-Isopropyl-1H-pyrrol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1-isopropyl-1H-pyrrol-3-yl)ethanone; 1-(1-Isopropylpyrrol-3-yl)-2,2,2-trifluoroethanone; 3-Trifluoroacetyl-1-isopropylpyrrole; Trifluoro(1-isopropyl-1H-pyrrol-3-yl)methanone; 74889-34-2 (CAS); TFIP
EINECS	Contact for details

Quality Control

Our production of Ethanone, 2,2,2-Trifluoro-1-[1-(1-Methylethyl)-1H-Pyrrol-3-Yl]- adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request, guaranteeing traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.