Description

(4S,5S)-5-(Acetyloxy)-2-Ethyl-1,3,2-Dioxaborinane-4-Methanol Acetate CAS NO 74841-62-6 is a high-purity, chiral boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a protected form of a key boronic acid intermediate, enabling precise stereocontrol in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those requiring Suzuki-Miyaura cross-coupling reactions.
• Asymmetric Synthesis: Used as a stereodefined building block for constructing molecules with specific three-dimensional configurations in medicinal chemistry.
• Boronic Acid Prodrug: Serves as a protected, stable form of a reactive boronic acid, facilitating handling and storage before deprotection in the final synthetic steps.
• Organic Electronics Research: Potential monomer or intermediate in the development of novel organic semiconductors and electronic materials.
• Catalyst Ligand Synthesis: Can be utilized to create novel chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Employed in the development of tools for studying biological processes involving boron chemistry.

Basic Information

Product Name	(4S,5S)-5-(Acetyloxy)-2-Ethyl-1,3,2-Dioxaborinane-4-Methanol Acetate
CAS No.	74841-62-6
Molecular Formula	C10H17BO6
Molecular Weight	244.05 g/mol
Synonyms	(4S,5S)-2-Ethyl-4-(hydroxymethyl)-1,3,2-dioxaborinane-5-yl acetate; (4S,5S)-5-(Acetyloxy)-2-ethyl-1,3,2-dioxaborinane-4-methanol acetate; (4S-cis)-2-Ethyl-4-(hydroxymethyl)-1,3,2-dioxaborinane-5-yl acetate; (4S,5S)-2-Ethyl-4-(hydroxymethyl)-1,3,2-dioxaborinane-5-ol acetate; Chiral boronic ester acetate; Acetylated boronate ester
EINECS	Contact for details

Quality Control

Our (4S,5S)-5-(Acetyloxy)-2-Ethyl-1,3,2-Dioxaborinane-4-Methanol Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or clear colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.