Description

1-O,3-O:2-O,4-o-Bis(Phenylboranediyl)-D-Glucitol 5,6-Diacetate is a specialized organoboron derivative of D-glucitol, a sugar alcohol. This compound is valued for its role as a key chiral intermediate and protecting group reagent in sophisticated organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries for the stereoselective construction of complex molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry.
• Asymmetric Catalysis & Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalytic reactions, enabling the production of enantiomerically pure compounds.
• Carbohydrate Chemistry & Glycoconjugate Research: Acts as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides or glycoconjugates.
• Boronic Acid Ester Chemistry: Functions as a diol-protecting group via boronate ester formation, offering reversible protection in multi-step synthetic pathways.
• Material Science Research: Investigated for potential use in creating novel polymeric materials or sensors due to its boronate ester functionality.
• Academic & Industrial R&D: Employed in exploratory chemistry for method development and the synthesis of novel chemical entities.

Basic Information

Product Name	1-O,3-O:2-O,4-o-Bis(Phenylboranediyl)-D-Glucitol 5,6-Diacetate
CAS No.	74825-22-2
Molecular Formula	C22H24B2O8
Molecular Weight	437.85 g/mol
Synonyms	D-Glucitol, 1,3:2,4-bis-O-[(R)-phenylboranediyl]-, 5,6-diacetate; 1,3:2,4-Bis-O-[(R)-phenylboranediyl]-D-glucitol 5,6-diacetate; (3aR,5R,6S,6aR)-5-(Acetyloxy)-2,2-diphenyl-6-[(acetyloxy)methyl]tetrahydro-3aH-1,3,2λ4-dioxaborolo[4,5-d][1,3,2λ4]dioxaborole; D-Glucitol 1,3:2,4-bis(phenylboronate) 5,6-diacetate; Phenylboronic Acid D-Glucitol Diacetonide Diacetate Derivative
EINECS	Contact for details

Quality Control

Our high-purity organoboron compounds are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement to ensure chiral integrity. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.