Description

2-O,4-o-(Phenylboranediyl)-D-Ribose is a sophisticated ribose derivative featuring a phenylboronate protecting group, which is critical for selective chemical transformations in complex synthesis. This compound is valued for its role as a key chiral building block and protecting group strategy in nucleoside and carbohydrate chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of antiviral agents, nucleotide analogs, and other bioactive molecules.

Application

• Nucleoside & Nucleotide Analog Synthesis: Serves as a crucial protected intermediate in the multi-step synthesis of modified nucleosides for antiviral and anticancer research.
• Carbohydrate Chemistry: Used as a specialized building block for constructing complex oligosaccharides and glycomimetics with precise stereochemistry.
• Pharmaceutical Intermediate: Acts as a high-value precursor in the research and development (R&D) phase of novel therapeutic agents, particularly those targeting RNA viruses.
• Protecting Group Strategy: The phenylboranediyl group provides selective protection for specific hydroxyl groups on the ribose ring, enabling controlled sequential reactions.
• Bioconjugation & Probe Development: Utilized in the creation of labeled nucleotides or carbohydrate-based probes for biochemical and diagnostic applications.
• Academic & Industrial Research: Essential for synthetic organic chemists in both university and corporate R&D settings exploring new reaction methodologies and bioactive compound libraries.

Basic Information

Product Name	2-O,4-o-(Phenylboranediyl)-D-Ribose
CAS No.	74810-59-6
Molecular Formula	C11H13BO5
Molecular Weight	236.03 g/mol
Synonyms	D-Ribose, 2,4-(phenylboranediyl)-; 2,4-O-(Phenylboranediyl)-D-ribose; 2,4-O-Phenylboranediyl-D-ribose; Phenylboronic Acid D-Ribose 2,4-Cyclic Ester; 2,4-Cyclic Phenylboronate Ester of D-Ribose; 74810-59-6; D-Ribose cyclic phenylboronate (2,4)
EINECS	Contact for details

Quality Control

Our 2-O,4-o-(Phenylboranediyl)-D-Ribose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by advanced analytical techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.