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Ethyl(2-Cyclohexylidene-1,1-Diethylpropyl)(Trimethylsilyloxy)Borane CAS NO 74810-48-3


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CAS No.:74810-48-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl(2-Cyclohexylidene-1,1-Diethylpropyl)(Trimethylsilyloxy)Borane is a specialized organoboron reagent featuring a unique sterically hindered structure. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the formation of complex carbon-boron bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in boron-containing drug discovery programs.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate boron-based functional groups.
  • Advanced Material Precursor: Serves as a precursor for boron-doped organic semiconductors, liquid crystals, and other functional materials.
  • Cross-Coupling Reactions: Acts as an organoboron reagent in Suzuki-Miyaura and other transition metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
  • Asymmetric Synthesis: Employed in stereoselective synthesis due to its chiral and sterically demanding environment.
  • Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Item Detail
Product Name Ethyl(2-Cyclohexylidene-1,1-Diethylpropyl)(Trimethylsilyloxy)Borane
CAS No. 74810-48-3
Molecular Formula C16H33BOSi
Molecular Weight 280.33 g/mol
Synonyms Ethyl(2-cyclohexylidene-1,1-diethylpropyl)(trimethylsilyloxy)borane; (Trimethylsilyloxy)[ethyl(2-cyclohexylidene-1,1-diethylpropyl)]borane; Borane, [ethyl(2-cyclohexylidene-1,1-diethylpropyl)](trimethylsilyloxy)-; TMS-protected organoboronic ester derivative
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Quality Control

Our Ethyl(2-Cyclohexylidene-1,1-Diethylpropyl)(Trimethylsilyloxy)Borane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and chromatographic methods (GC/HPLC), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C to maintain stability. This compound is moisture-sensitive and easily oxidized; prolonged exposure to air or ambient humidity should be avoided.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (NMR) Conforms to structure
Purity (GC/HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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