Description

1-O,2-O:3-O,4-o-Bis(Phenylboranediyl)-α-D-Ribopyranose is a specialized organoboron compound that functions as a protected ribose derivative, crucial for synthetic organic and medicinal chemistry. Its core value lies in enabling precise, high-yield glycosylation and nucleotide synthesis by protecting reactive hydroxyl groups on the ribose sugar scaffold. This chemical is essential for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of nucleoside analogs, antiviral agents, and complex carbohydrate-based molecules.

Application

• Nucleoside & Nucleotide Synthesis: A key protected intermediate for constructing ribose-containing nucleosides and their analogs.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Carbohydrate Chemistry: Serves as a building block for the synthesis of complex oligosaccharides and glycoconjugates.
• Medicinal Chemistry & Library Synthesis: Enables the creation of diverse compound libraries for screening against biological targets.
• Process Chemistry & Scale-up: Employed in the development of robust, scalable synthetic routes for pharmaceutical manufacturing.
• Bioconjugation & Probe Development: Useful for attaching reporter groups or other molecules to sugar moieties in biochemical tools.

Basic Information

Product Name	1-O,2-O:3-O,4-o-Bis(Phenylboranediyl)-α-D-Ribopyranose
CAS No.	74810-33-6
Molecular Formula	C17H17B2O4
Molecular Weight	313.94 g/mol
Synonyms	1,2:3,4-Bis-O-(phenylboranediyl)-α-D-ribopyranose; α-D-Ribopyranose, 1,2:3,4-bis-O-(phenylboranediyl)-; 1,2:3,4-Di-O-phenylboranyl-α-D-ribopyranose; Phenylboronic Acid Ribose Ester Derivative; Ribose Phenylboronate; 1,2:3,4-Bis(phenylboronate) of α-D-Ribose
EINECS	Contact for details

Quality Control

Our 1-O,2-O:3-O,4-o-Bis(Phenylboranediyl)-α-D-Ribopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.