Description

(S)-[(S)-2-Phenyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol is a chiral, enantiomerically pure boronic ester derivative of 1,2-ethanediol. This compound matters as a sophisticated chiral building block and ligand, enabling precise stereochemical control in advanced synthetic chemistry. It is primarily needed by research and development teams in the pharmaceutical industry for asymmetric synthesis, as well as by fine chemical manufacturers producing high-value intermediates for active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Chiral Ligand in Asymmetric Catalysis: Utilized in transition metal-catalyzed reactions, such as asymmetric hydrogenation or cross-coupling, to induce high enantioselectivity.
• Building Block for Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of complex, stereochemically defined molecules for drug discovery and development.
• Synthesis of Boron-Containing Compounds: Used to introduce the boronate functional group into target molecules for further transformations like Suzuki-Miyaura cross-coupling.
• Agrochemical Research: Employed in the development of enantiomerically pure active ingredients for herbicides, fungicides, or insecticides.
• Material Science Research: Potential application in the development of chiral organic frameworks or polymers with specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and catalysis within university and corporate laboratories.

Basic Information

Product Name	(S)-[(S)-2-Phenyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol
CAS No.	74807-80-0
Molecular Formula	C10H13BO4
Molecular Weight	208.02 g/mol
Synonyms	(S,S)-2-Phenyl-4-(hydroxymethyl)-1,3,2-dioxaborolane; (4S)-4-(Hydroxymethyl)-2-phenyl-1,3,2-dioxaborolane; (S)-2-Phenyl-4-(hydroxymethyl)-1,3,2-dioxaborolane; (S)-4-(Hydroxymethyl)-2-phenyl-1,3,2-dioxaborolane; (S)-1,2-Dihydroxyethyl (S)-2-phenyl-1,3,2-dioxaborolane-4-carboxylate (tautomeric form); Chiral phenylboronic ester diol; (S,S)-Phenylboronate of 1,2-ethanediol
EINECS	Contact for details

Quality Control

Our (S)-[(S)-2-Phenyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity, critical for sensitive asymmetric synthesis. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed and allowed to equilibrate to room temperature before opening to prevent condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.