Description

(E)-3-(2-Ethyl-1,3,2-Dioxaborolane-4-Yl)Propenal is a versatile and reactive organoboron building block, specifically an α,β-unsaturated aldehyde containing a cyclic dioxaborolane protecting group. This compound matters for its unique bifunctional reactivity, offering both an aldehyde and a protected boronic acid moiety, which is crucial for advanced synthetic transformations. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for coupling reactions to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boron-containing scaffolds.
• Materials Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester functionality is readily deprotected and utilized in palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via sequential reactions of the aldehyde and boronate groups.
• Ligand and Catalyst Development: Acts as a precursor for creating novel bidentate or tridentate ligands used in catalysis.

Basic Information

Item	Detail
Product Name	(E)-3-(2-Ethyl-1,3,2-Dioxaborolane-4-Yl)Propenal
CAS No.	74807-48-0
Molecular Formula	C8H13BO3
Molecular Weight	168.00 g/mol
Synonyms	(E)-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acrylaldehyde; 2-(2-Ethyl-1,3,2-dioxaborolan-4-yl)acrolein; 3-(2-Ethyl-1,3,2-dioxaborolan-4-yl)propenal; trans-3-(2-Ethyl-1,3,2-dioxaborolane-4-yl)acrylaldehyde; Acrolein, 3-(2-ethyl-1,3,2-dioxaborolan-4-yl)-, (E)-; Boronic acid, B-[2-(1,3-dioxolan-2-yl)ethenyl]-, 2-ethyl ester
EINECS	Contact for details

Quality Control

Our (E)-3-(2-Ethyl-1,3,2-Dioxaborolane-4-Yl)Propenal undergoes rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We employ advanced analytical techniques, including HPLC, NMR, and GC, to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing batch-specific data to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.