Description

(6R)-6,7,8,8A-Tetrahydro-6-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2(1H)-One is a high-purity, stereochemically defined intermediate of significant interest in advanced organic synthesis. This compound is valued for its complex decalin-based structure, which serves as a versatile chiral building block for the construction of more complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in process chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex natural product derivatives.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex molecular architectures in custom synthesis and process development.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fragrance and Flavor Chemistry: Potential intermediate in the synthesis of high-value, structurally complex fragrance compounds due to its terpenoid-like backbone.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry, including cyclization and stereoselective transformation reactions.

Basic Information

Product Name	(6R)-6,7,8,8A-Tetrahydro-6-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2(1H)-One
CAS No.	74799-42-1
Molecular Formula	C15H24O2
Molecular Weight	236.35 g/mol
Synonyms	(6R)-6,7,8,8a-Tetrahydro-6-(1-hydroxy-1-methylethyl)-4,8aα-dimethyl-2(1H)-naphthalenone; (6R)-6-(2-Hydroxypropan-2-yl)-4,8aα-dimethyl-1,2,3,6,7,8-hexahydronaphthalen-2-one; (6R)-6-(1-Hydroxy-1-methylethyl)-4,8aα-dimethyl-3,4,6,7,8,8a-hexahydro-1H-naphthalen-2-one; (6R)-6-(2-Hydroxy-2-propyl)-4,8aα-dimethyl-3,4,6,7,8,8a-hexahydro-1H-naphthalen-2-one; Decalinone derivative; Chiral decalone intermediate.
EINECS	Contact for details

Quality Control

Our (6R)-6,7,8,8A-Tetrahydro-6-(1-Hydroxy-1-Methylethyl)-4,8Aα-Dimethylnaphthalen-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.