Description

(3As,6Ar)-2-Ethyltetrahydrofuro[3,4-D]-1,3,2-Dioxaborole is a specialized organoboron compound, specifically a cyclic boronic ester. This chemical is valued as a crucial chiral building block and reagent in advanced organic synthesis, particularly for the formation of carbon-boron bonds. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules. Its unique fused-ring structure offers distinct stereochemical control in asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for boron-containing drugs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a protected boronic acid equivalent for palladium-catalyzed cross-coupling to form biaryl and other carbon-carbon bonds.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor to induce stereoselectivity in the creation of complex organic molecules.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides that incorporate boron chemistry.
• Material Science: Investigated as a monomer or additive for creating novel polymers with specific thermal or electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis research.

Basic Information

Product Name	(3As,6Ar)-2-Ethyltetrahydrofuro[3,4-D]-1,3,2-Dioxaborole
CAS No.	74793-57-0
Molecular Formula	C8H13BO3
Molecular Weight	168.00 g/mol
Synonyms	2-Ethyl-4,4,5,5-tetrahydrofuro[3,4-d][1,3,2]dioxaborole; (3aR,6aR)-2-Ethyltetrahydro-4H-furo[3,4-d][1,3,2]dioxaborole; Ethyl Furodioxaborole; Chiral Ethyl Boronate Ester; Tetrahydrofurodioxaborole Derivative; (R,R)-2-Ethyl-4,4,5,5-tetrahydrofuro[3,4-d][1,3,2]dioxaborole
EINECS	Contact for details

Quality Control

Our (3As,6Ar)-2-Ethyltetrahydrofuro[3,4-D]-1,3,2-Dioxaborole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical purity, verified by techniques such as HPLC, GC, and NMR. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.