Description

(S)-1-[(S)-2-Ethyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol Diacetate is a high-purity, chiral boronic ester derivative that serves as a critical synthetic intermediate. Its value lies in providing a protected, enantiomerically pure diol functionality, enabling precise stereocontrol in complex organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced chiral ligands.

Application

• Pharmaceutical Intermediate: Key building block in the asymmetric synthesis of complex drug molecules, especially those requiring specific stereochemistry.
• Chiral Ligand Synthesis: Used to prepare enantiomerically pure ligands for catalysis in asymmetric hydrogenation and cross-coupling reactions.
• Advanced Material Research: Serves as a precursor for boron-containing polymers and functional materials with specialized optical or electronic properties.
• Organic Synthesis Reagent: Provides a protected diol moiety for multi-step synthesis, facilitating the construction of natural products and complex molecular architectures.
• Agrochemical Development: Employed in the research and synthesis of novel, stereospecific pesticides and herbicides.

Basic Information

Product Name	(S)-1-[(S)-2-Ethyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol Diacetate
CAS No.	74793-27-4
Molecular Formula	C10H17BO6
Molecular Weight	244.05 g/mol
Synonyms	(S,S)-1,2-Ethanediol, 1-[(S)-2-ethyl-1,3,2-dioxaborolan-4-yl]-, diacetate; (4S)-2-Ethyl-4-[(1S)-1,2-diacetoxyethyl]-1,3,2-dioxaborolane; (S)-1-[(S)-2-Ethyl-1,3,2-dioxaborolan-4-yl]ethane-1,2-diyl diacetate; (S,S)-Ethylboronate diacetate; Chiral ethyl dioxaborolane diacetate; B-ethyl-4-(1,2-diacetoxyethyl)-1,3,2-dioxaborolane (S,S-isomer)
EINECS	Contact for details

Quality Control

Our (S)-1-[(S)-2-Ethyl-1,3,2-Dioxaborolan-4-Yl]-1,2-Ethanediol Diacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and NMR spectroscopy, to ensure compliance with exacting standards for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.