Description

(4S)-2-Ethyl-1,3,2-Dioxaborolane-4β,5α-Dimethanol Dibenzoate CAS NO 74793-25-2 is a high-purity, chiral boronic ester derivative, serving as a critical chiral building block and ligand in advanced organic synthesis. Its value lies in enabling precise stereochemical control in the construction of complex molecules, which is essential for developing pharmaceuticals and specialty materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications in asymmetric synthesis and catalysis.

Application

• As a chiral auxiliary or ligand in asymmetric catalytic reactions, including Suzuki-Miyaura cross-couplings.
• As a key synthetic intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• For the preparation of stereodefined boronic acid derivatives used in medicinal chemistry and drug discovery programs.
• In the synthesis of complex natural products and specialty agrochemicals requiring high enantiomeric purity.
• As a building block for advanced materials science, including the development of chiral polymers or sensors.

Basic Information

Product Name	(4S)-2-Ethyl-1,3,2-Dioxaborolane-4β,5α-Dimethanol Dibenzoate
CAS No.	74793-25-2
Molecular Formula	C21H23BO6
Molecular Weight	382.21 g/mol
Synonyms	(4S)-2-Ethyl-4,5-bis(hydroxymethyl)-1,3,2-dioxaborolane dibenzoate; (4S)-4,5-Bis(benzoyloxymethyl)-2-ethyl-1,3,2-dioxaborolane; (S)-2-Ethyl-4,5-bis(hydroxymethyl)-1,3,2-dioxaborolane dibenzoate; (S)-4,5-Bis(benzoyloxymethyl)-2-ethyl-1,3,2-dioxaborolane; Chiral Ethyl Boronate Dibenzoate; (4S)-2-Ethyl-1,3,2-dioxaborolane-4,5-dimethanol dibenzoate
EINECS	Contact for details

Quality Control

Our (4S)-2-Ethyl-1,3,2-Dioxaborolane-4β,5α-Dimethanol Dibenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and GC/MS, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.