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1-O,2-o-(Ethylboranediyl)-5-o-(Diethylboryl)-α-D-Glucofuranuronic Acid γ-Lactone CAS NO 74779-81-0


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CAS No.:74779-81-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-O,2-o-(Ethylboranediyl)-5-o-(Diethylboryl)-α-D-Glucofuranuronic Acid γ-Lactone is a specialized organoboron compound derived from a glucofuranuronic acid lactone scaffold, serving as a key intermediate in advanced synthetic chemistry. This compound is valued for its unique structure, which incorporates multiple boron centers, making it a versatile precursor for the development of novel carbohydrate-based materials and bioactive molecules. It is primarily sought by research institutions and industrial R&D departments focused on pharmaceutical development, carbohydrate chemistry, and materials science.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of boron-containing drug candidates, particularly for boron neutron capture therapy (BNCT) and enzyme inhibitors.
  • Carbohydrate Chemistry Research: Used as a model compound or precursor for studying the modification and functionalization of sugar molecules with boron-based protecting groups or ligands.
  • Materials Science: Acts as a monomer or cross-linking agent in the development of novel polymeric materials with specific optical or electronic properties.
  • Chemical Synthesis: Employed as a specialized reagent in organic synthesis for introducing boron functionalities into complex molecular architectures.
  • Analytical Standard: Utilized as a reference standard in chromatographic and spectroscopic methods for quality control and research purposes.

Basic Information

Item Details
Product Name 1-O,2-o-(Ethylboranediyl)-5-o-(Diethylboryl)-α-D-Glucofuranuronic Acid γ-Lactone
CAS No. 74779-81-0
Molecular Formula C14H23B2O7
Molecular Weight 324.95 g/mol
Synonyms 1-O,2-O-(Ethylboranediyl)-5-O-(diethylboryl)-α-D-glucofuranuronic acid γ-lactone; α-D-Glucofuranuronic acid, 1,2-O-(ethylboranediyl)-5-O-(diethylboryl)-, γ-lactone; Glucofuranuronic acid γ-lactone boron derivative; Ethylboranediyl-diethylboryl glucofuranuronolactone; Boronated glucofuranuronic acid lactone; (2R,3S,4R,5R)-5-[(Diethylboryl)oxy]-2-[(ethylborylene)oxy]tetrahydro-2H-furo[2,3-d][1,3,2]dioxaborole-4-carboxylic acid γ-lactone
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Quality Control

Our production of 1-O,2-o-(Ethylboranediyl)-5-o-(Diethylboryl)-α-D-Glucofuranuronic Acid γ-Lactone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (¹H, ¹¹B, ¹³C), and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and research-grade standards to meet the precise requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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