Description

2-O,3-O:4-O,6-o-Bis(Ethylboranediyl)-1-o-(Diethylboryl)-α-L-Sorbofuranose is a sophisticated organoboron derivative of L-sorbose, a sugar molecule. This compound is valued as a key chiral intermediate and protecting group reagent in advanced synthetic organic chemistry, particularly for its ability to form stable cyclic boronates with diols. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, stereochemically defined molecules such as nucleoside analogs, carbohydrate-based drugs, and other bioactive compounds.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a building block for the production of novel antiviral and anticancer agents, especially nucleoside analogs.
• Protecting Group Reagent: Used to selectively protect cis-diol groups on sugar molecules and other polyhydroxylated compounds during multi-step syntheses.
• Asymmetric Synthesis Catalyst/Precursor: Can be utilized in the development of boron-based catalysts for asymmetric transformations.
• Research & Development: A critical tool in academic and industrial R&D for exploring new synthetic routes to complex natural products and bioactive molecules.
• Fine Chemical Manufacturing: Employed in the custom synthesis of high-value, specialty chemicals for the life sciences industry.
• Glycochemistry and Carbohydrate Chemistry: Facilitates the modification and functionalization of sugar scaffolds for drug discovery and biochemical studies.

Basic Information

Item	Detail
Product Name	2-O,3-O:4-O,6-o-Bis(Ethylboranediyl)-1-o-(Diethylboryl)-α-L-Sorbofuranose
CAS No.	74779-78-5
Molecular Formula	C16H30B3O6
Molecular Weight	356.83 g/mol
Synonyms	1-O-(Diethylboryl)-2,3:4,6-bis-O-(ethylboranediyl)-α-L-sorbofuranose; α-L-Sorbofuranose, 2,3:4,6-bis-O-(ethylboranediyl)-1-O-(diethylboryl)-; L-Sorbose cyclic diethyl boronate (triethylboron derivative); Sorbose triethylboron complex; Organoboron sorbose derivative; Ethylboronate-protected L-sorbose; Boronic ester of L-sorbose.
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O:4-O,6-o-Bis(Ethylboranediyl)-1-o-(Diethylboryl)-α-L-Sorbofuranose is produced and tested under strict quality management protocols to ensure high purity, consistency, and reliability for sensitive synthetic applications. Our quality assurance includes comprehensive analytical characterization. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.