Description

(4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane]-5,5'-Dione is a high-purity, chiral bidentate boronate ester compound. This advanced intermediate is critical for applications requiring precise stereochemical control, particularly in asymmetric synthesis and catalysis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, especially for active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in enantioselective transformations, such as Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel, stereochemically defined pesticides and herbicides.
• Material Science Research: Employed in the development of advanced organic electronic materials and polymers where boronate esters are functional components.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of sensors or probes due to its reactive boronate functionality.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis within university and corporate research laboratories.

Basic Information

Product Name	(4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane]-5,5'-Dione
CAS No.	74742-40-8
Molecular Formula	C12H18B2O6
Molecular Weight	279.89 g/mol
Synonyms	(4R,4'S)-2,2'-Diethyl-4,4'-bi-1,3,2-dioxaborolane-5,5'-dione; (R,R)-2,2'-Diethyl-4,4'-bi(1,3,2-dioxaborolane)-5,5'-dione; Diethyl Tartrate Boronate; Tartaric Acid Derived Bis(Boronate) Ester; Chiral Dioxaborolane Dione; (R,R)-Tartrate Bis(Boronic Ester); 74742-40-8; (4R,4'S)-Diethyl Tartrate Bis(Boronate)
EINECS	Contact for details

Quality Control

Our (4R,4'S)-2,2'-Diethyl-4,4'-Bi[1,3,2-Dioxaborolane]-5,5'-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee product identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.