Description

3,5-o-Benzylidene-1,2-o-Isopropylideneglucofuranose is a key protected carbohydrate intermediate used in sophisticated organic synthesis. This compound is valued for its role as a versatile chiral building block, enabling the stereoselective construction of complex molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where precise control over sugar moiety chemistry is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified nucleosides and nucleotide analogs for antiviral and anticancer research.
• Chiral Building Block: Used in asymmetric synthesis to introduce stereochemically defined carbohydrate units into complex target molecules.
• Glycochemistry Research: Serves as a protected glucofuranose derivative for studying glycosylation reactions and synthesizing oligosaccharides.
• Medicinal Chemistry: Employed in the discovery and development of new therapeutic agents that target sugar-processing enzymes or pathways.
• Process Chemistry: Used in scaling up routes to active pharmaceutical ingredients (APIs) that contain specialized sugar components.
• Academic & Industrial R&D: A valuable reagent for chemists exploring new synthetic methodologies and carbohydrate-based materials.

Basic Information

Product Name	3,5-o-Benzylidene-1,2-o-Isopropylideneglucofuranose
CAS No.	74708-51-3
Molecular Formula	C₁₆H₂₀O₆
Molecular Weight	308.33 g/mol
Synonyms	1,2-O-Isopropylidene-3,5-O-benzylidene-α-D-glucofuranose; 3,5-O-Benzylidene-1,2-O-isopropylidene-α-D-glucofuranose; 1,2:3,5-Di-O-benzylidene-α-D-glucofuranose (incorrect but common alias); D-Glucofuranose, 3,5-O-benzylidene-1,2-O-(1-methylethylidene)-; Benzylidene Isopropylidene Glucofuranose; Protected Glucofuranose Derivative
EINECS	Contact for details

Quality Control

Our 3,5-o-Benzylidene-1,2-o-Isopropylideneglucofuranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, optical rotation, and impurity profiles. Our quality commitment aligns with the standards expected in fine chemical and pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]₂₀D	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.