Description

1-Azaspiro(5.5)Undecan-8-Ol, 7-Butyl-2-(4-Pentenyl)-, (6R-(6Alpha(R*), 7Beta,8Alpha))- is a complex, stereochemically defined spirocyclic amine alcohol building block of significant interest in advanced organic synthesis. Its intricate molecular architecture, featuring multiple chiral centers and functional groups, makes it a high-value intermediate for constructing sophisticated pharmacophores and fine chemicals. This compound is primarily sought after by pharmaceutical R&D and custom synthesis organizations for developing novel active ingredients and complex molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Advanced Organic Synthesis: Used in the construction of complex spirocyclic and polycyclic frameworks for novel chemical entities in medicinal chemistry.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for enantioselective synthesis.
• Agrochemical Development: Potential intermediate for creating novel, high-specificity active ingredients for crop protection.
• Academic & Institutional Research: Utilized in universities and research institutes for studying stereochemistry, reaction mechanisms, and new synthetic methodologies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1-Azaspiro(5.5)Undecan-8-Ol, 7-Butyl-2-(4-Pentenyl)-, (6R-(6Alpha(R*), 7Beta,8Alpha))-
CAS No.	74674-96-7
Molecular Formula	C18H33NO
Molecular Weight	279.46 g/mol
Synonyms	(6R,7S,8R)-7-Butyl-2-(pent-4-en-1-yl)-1-azaspiro[5.5]undecan-8-ol; 7-Butyl-2-(4-pentenyl)-1-azaspiro[5.5]undecan-8-ol, (6R-(6alpha(R*),7beta,8alpha))-; (6R-(6alpha(R*),7beta,8alpha))-7-Butyl-2-(4-pentenyl)-1-azaspiro[5.5]undecan-8-ol; 1-Azaspiro[5.5]undecan-8-ol, 7-butyl-2-(4-pentenyl)-, [6R-[6alpha(R*),7beta,8alpha]]-; Stereoisomer of spirocyclic amino alcohol 74674-96-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support development and commercial projects requiring compliance with cGMP and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.