Description

1-(2-Ethyl-4,4,6-Trimethyl-1,3,2-Dioxaborinan-5-Yl)Ethanone is a specialized organoboron compound, a key intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical and advanced material research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to leverage boron chemistry for novel product development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating boron for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a protected boronic ester reagent for forming carbon-carbon bonds, a fundamental step in creating complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Catalyst and Ligand Development: Acts as a starting material for synthesizing novel boron-containing catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	1-(2-Ethyl-4,4,6-Trimethyl-1,3,2-Dioxaborinan-5-Yl)Ethanone
CAS No.	74663-80-2
Molecular Formula	C11H21BO3
Molecular Weight	212.10 g/mol
Synonyms	5-Acetyl-2-ethyl-4,4,6-trimethyl-1,3,2-dioxaborinane; 2-Ethyl-4,4,6-trimethyl-5-acetyl-1,3,2-dioxaborinane; 1-(2-Ethyl-4,4,6-trimethyl-1,3,2-dioxaborinan-5-yl)ethan-1-one; Acetyl-protected boronic ester; Boronic ester intermediate; 74663-80-2; Ethyl-trimethyl-dioxaborinane acetyl derivative
EINECS	Contact for details

Quality Control

Our 1-(2-Ethyl-4,4,6-Trimethyl-1,3,2-Dioxaborinan-5-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and process applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.