Description

1-[2-Ethyl-4-Methyl-5-(1-Methylethenyl)-1,3,2-Dioxaborolan-4-Yl]Ethanone is a specialized organoboron compound featuring a dioxaborolane ring, which serves as a key intermediate in advanced organic synthesis. Its value lies in its unique structure, which provides a protected boronic ester functionality that is crucial for modern cross-coupling reactions, enabling the construction of complex molecular architectures. This high-purity chemical is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality building blocks for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to form biaryl and other carbon-carbon bonds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific boron-containing motifs for enhanced activity.
• Materials Science Research: Serves as a precursor for developing advanced organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that utilize boron chemistry for labeling or binding studies.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.
• Ligand & Catalyst Preparation: Used in the synthesis of novel ligands and catalysts where the dioxaborolane group modifies electronic properties or solubility.

Basic Information

Product Name	1-[2-Ethyl-4-Methyl-5-(1-Methylethenyl)-1,3,2-Dioxaborolan-4-Yl]Ethanone
CAS No.	74646-09-6
Molecular Formula	C₁₁H₁₉BO₃
Molecular Weight	210.08 g/mol
Synonyms	4-Acetyl-2-ethyl-4-methyl-5-(1-methylethenyl)-1,3,2-dioxaborolane; 2-Ethyl-4-methyl-5-(prop-1-en-2-yl)-4-acetyl-1,3,2-dioxaborolane; 1-[2-Ethyl-4-methyl-5-(prop-1-en-2-yl)-1,3,2-dioxaborolan-4-yl]ethan-1-one; Acetyl-substituted dioxaborolane; Boronic ester intermediate 74646-09-6; 4-Acetyl-2-ethyl-4-methyl-5-isopropenyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 1-[2-Ethyl-4-Methyl-5-(1-Methylethenyl)-1,3,2-Dioxaborolan-4-Yl]Ethanone adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and GC analysis, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.