Description

2-Ethyl-5-Methyl-4-Phenyl-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, valued for its role as a versatile synthetic intermediate. Its structure makes it a crucial reagent in modern cross-coupling reactions, enabling the efficient construction of complex molecules. This chemical is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel carbon-carbon bonds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for palladium-catalyzed coupling with aryl/vinyl halides to form biaryl and styrene derivatives, fundamental in pharmaceutical and material science synthesis.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex, sterically hindered aromatic systems.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Used to synthesize novel bidentate or polydentate ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: A monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal or electronic properties.

Basic Information

Product Name	2-Ethyl-5-Methyl-4-Phenyl-1,3,2-Dioxaborinane
CAS No.	74646-03-0
Molecular Formula	C13H17BO2
Molecular Weight	216.09 g/mol
Synonyms	4-Phenyl-2-ethyl-5-methyl-1,3,2-dioxaborinane; 2-Ethyl-5-methyl-4-phenyl-1,3,2-dioxaborinane; 2-Ethyl-4-phenyl-5-methyl-1,3,2-dioxaborinane; 1,3,2-Dioxaborinane, 2-ethyl-5-methyl-4-phenyl-; (2-Ethyl-5-methyl-1,3,2-dioxaborinan-4-yl)benzene; Cyclic phenylboronic ester
EINECS	Contact for details

Quality Control

Our 2-Ethyl-5-Methyl-4-Phenyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be kept under an inert atmosphere (nitrogen or argon) for long-term storage to prevent potential hydrolysis or oxidation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
¹H NMR Purity	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.