Description

(1Ar,2As)-2A,3,4,5,6,6A,7,7A-Octahydro-7β-Hydroxymethyl-3,3,6Aβ,7Aα-Tetramethylnaphth[2,3-B]Oxiren-2(1Ah)-One is a complex, high-purity oxirane derivative with a fused naphthalene ring system, offering a unique sterically hindered epoxide functionality. This compound is valued as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in steroid-like or terpenoid-based therapeutic areas.
• Fine Chemical Synthesis: Used as a versatile electrophile in the construction of complex molecular architectures for agrochemicals, flavors, and fragrances.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems due to its defined stereochemistry.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for chemists exploring new reaction methodologies, total synthesis, and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(1Ar,2As)-2A,3,4,5,6,6A,7,7A-Octahydro-7β-Hydroxymethyl-3,3,6Aβ,7Aα-Tetramethylnaphth[2,3-B]Oxiren-2(1Ah)-One
CAS No.	74636-06-9
Molecular Formula	C₁₇H₂₆O₃
Molecular Weight	278.39 g/mol
Synonyms	7β-Hydroxymethyl-3,3,6aβ,7aα-tetramethylperhydronaphtho[2,3-b]oxirene-2(1aH)-one; (1aR,2aS)-2a,3,4,5,6,6a,7,7a-Octahydro-7β-(hydroxymethyl)-3,3,6aβ,7aα-tetramethylnaphth[2,3-b]oxiren-2(1aH)-one; Tetramethylnaphthoxirenone derivative; CAS 74636-06-9; Oxirane, 2-(hydroxymethyl)-2,4a,5,6,7,8,9,9a-octahydro-3,5,5,9a-tetramethyl-, (2R,4aS,9aS)-; (1aR,2aS)-rel-(+)-2a,3,4,5,6,6a,7,7a-Octahydro-7β-(hydroxymethyl)-3,3,6aβ,7aα-tetramethylnaphth[2,3-b]oxiren-2(1aH)-one
EINECS	Contact for details

Quality Control

Our (1Ar,2As)-2A,3,4,5,6,6A,7,7A-Octahydro-7β-Hydroxymethyl-3,3,6Aβ,7Aα-Tetramethylnaphth[2,3-B]Oxiren-2(1Ah)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) with chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR, IR) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.