Description

3,4,5,5Aα,6,7-Hexahydro-3α-Hydroxy-7α-Methyl-5α-Isopropyl-8H-Naphtho[1,8-Bc]Furan-8-One is a high-purity, complex polycyclic furanone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of novel, structurally complex molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex drug candidates, particularly in steroid-like or terpenoid-based therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its complex polycyclic structure.
• Fine Chemical Production: Serves as a sophisticated building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysis or advanced polymeric materials with specific optical properties.

Basic Information

Product Name	3,4,5,5Aα,6,7-Hexahydro-3α-Hydroxy-7α-Methyl-5α-Isopropyl-8H-Naphtho[1,8-Bc]Furan-8-One
CAS No.	74635-99-7
Molecular Formula	C₁₆H₂₂O₃
Molecular Weight	262.34 g/mol
Synonyms	8H-Naphtho[1,8-bc]furan-8-one, 3,4,5,5aα,6,7-hexahydro-3α-hydroxy-7α-methyl-5α-(1-methylethyl)-; 5α-Isopropyl-3α-hydroxy-7α-methyl-3,4,5,5aα,6,7-hexahydro-8H-naphtho[1,8-bc]furan-8-one; Hexahydroxy-methyl-isopropyl-naphthofuranone; NSC 339586; Polycyclic furanone derivative; Chiral naphthofuranone intermediate.
EINECS	Contact for details

Quality Control

Our 3,4,5,5Aα,6,7-Hexahydro-3α-Hydroxy-7α-Methyl-5α-Isopropyl-8H-Naphtho[1,8-Bc]Furan-8-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting research and production standards. Comprehensive Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.