Description

2-Chloro-4-Methylbenzotrifluoride is a versatile halogenated aromatic building block characterized by its trifluoromethyl and chloro substituents, which confer unique electronic and steric properties. This compound is a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its structure enables precise molecular tuning. It is primarily sought after by research institutions and industrial manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors for developing novel compounds with enhanced performance characteristics.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved bioactivity and environmental stability.
• Pharmaceutical Synthesis: Serves as a crucial building block for creating pharmacologically active molecules, particularly in the development of compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Liquid Crystal & OLED Materials: Used in the production of advanced electronic display materials, where its aromatic core and halogen atoms contribute to desired electronic properties and molecular alignment.
• Polymer & Resin Modifier: Acts as a monomer or additive to introduce fluorine content into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions as a versatile electrophile in research and fine chemical production.
• Dye & Pigment Manufacturing: Utilized in the synthesis of specialized dyes and pigments where the chloro and trifluoromethyl groups alter color fastness and solubility.

Basic Information

Product Name	2-Chloro-4-Methylbenzotrifluoride
CAS No.	74483-46-8
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	1-Chloro-2-methyl-5-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-p-xylene; 2-Chloro-4-methyl-α,α,α-trifluorotoluene; 4-Methyl-2-chlorobenzotrifluoride; 2-Chloro-4-(trifluoromethyl)toluene; 5-Chloro-2-methylbenzotrifluoride; 2-Methyl-5-chlorobenzotrifluoride; Benzene, 1-chloro-2-methyl-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment to guarantee traceability and batch-to-batch consistency for your production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.35 g/cm³
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.