Description

2-Fluoro-4-Methoxyacetophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring both methoxy and fluoro substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies, leveraging its specific polarity and molecular geometry.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic applications.
• Chemical Research & Development: A valuable reagent for method development, catalysis studies, and the exploration of new fluorination reactions in academic and industrial laboratories.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis and the manufacture of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	2-Fluoro-4-Methoxyacetophenone
CAS No.	74457-86-6
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-(2-Fluoro-4-methoxyphenyl)ethanone; 2'-Fluoro-4'-methoxyacetophenone; 4-Methoxy-2-fluoroacetophenone; 2-Fluoro-4-methoxyacetophenone; 2-Fluoro-4'-methoxyacetophenone; Ethanone, 1-(2-fluoro-4-methoxyphenyl)-; 74457-86-6
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methoxyacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to quality assurance supports your regulatory needs and process reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.