Description

2-Ethyl-4-Methyl-4,6-Bis(1-Methylethyl)-4H-1,3,2-Dioxaborin is a specialized organoboron compound belonging to the 1,3,2-dioxaborinane class, valued for its role as a versatile synthetic intermediate and ligand precursor. Its unique sterically hindered structure makes it particularly useful in advanced organic synthesis, especially in cross-coupling reactions and the development of novel materials. This chemical is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for boron-containing drug candidates.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a boron reagent for forming carbon-carbon bonds, a fundamental step in creating complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate boron heterocycles.
• Ligand for Catalysis: Functions as a precursor for generating specialized ligands used in homogeneous catalysis to control reaction selectivity and efficiency.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where boron-based compounds can tune electronic properties.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new reaction pathways in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	2-Ethyl-4-Methyl-4,6-Bis(1-Methylethyl)-4H-1,3,2-Dioxaborin
CAS No.	74421-11-7
Molecular Formula	C12H23BO2
Molecular Weight	210.12 g/mol
Synonyms	2-Ethyl-4-methyl-4,6-diisopropyl-4H-1,3,2-dioxaborin; 4H-1,3,2-Dioxaborin, 2-ethyl-4-methyl-4,6-bis(1-methylethyl)-; 2-Ethyl-4-methyl-4,6-di(propan-2-yl)-4H-1,3,2-dioxaborinine; Diisopropylethylmethyl dioxaborinane; Boron, (2-ethyl-4-methyl-4,6-bis(1-methylethyl)-4H-1,3,2-dioxaborinato)-; Sterically hindered dioxaborinane; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Ethyl-4-Methyl-4,6-Bis(1-Methylethyl)-4H-1,3,2-Dioxaborin is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous demands of GMP and ISO-guided environments where traceability and documentation are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Density	~0.95 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.