Description

2-Trimethylsilyloxyoctadecanoic Acid Trimethylsilyl Ester is a high-purity, fully silylated derivative of stearic acid, designed for applications requiring moisture protection and enhanced volatility. This compound is critical for analytical chemistry and organic synthesis, where it acts as a versatile protecting group and derivatization agent to improve the gas chromatographic analysis of complex molecules. It is primarily utilized by research laboratories, pharmaceutical developers, and specialty chemical manufacturers working with fatty acids, lipids, and sensitive organic intermediates.

Application

• Gas Chromatography (GC) Derivatization: Used to convert polar carboxylic acids (like stearic acid) into volatile, thermally stable trimethylsilyl (TMS) esters for precise analysis.
• Organic Synthesis Intermediate: Serves as a protected form of stearic acid in multi-step synthetic routes, particularly in pharmaceutical and fine chemical production.
• Lipid and Metabolite Analysis: Essential in metabolomics and lipidomics research for the profiling and quantification of fatty acids and related metabolites.
• Protecting Group Chemistry: The silyl groups protect the carboxylic acid functionality from unwanted reactions during complex synthetic sequences.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in analytical laboratories.
• Material Science Research: Investigated for surface modification and as a precursor in the development of specialized silicone-based materials.

Basic Information

Product Name	2-Trimethylsilyloxyoctadecanoic Acid Trimethylsilyl Ester
CAS No.	74367-66-1
Molecular Formula	C24H52O3Si2
Molecular Weight	444.85 g/mol
Synonyms	Stearic Acid Bis(trimethylsilyl) Ester; Octadecanoic Acid, 2-(Trimethylsiloxy)-, Trimethylsilyl Ester; Bis(trimethylsilyl) 2-Trimethylsiloxyoctadecanoate; 2-TMS-Oxy Stearic Acid TMS Ester; TMS Stearate Derivative; 2-(Trimethylsiloxy)octadecanoic Acid Trimethylsilyl Ester; 74367-66-1; Stearic Acid TMS Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Trimethylsilyloxyoctadecanoic Acid Trimethylsilyl Ester is manufactured and tested under strict quality management systems. We ensure high chemical purity and consistency suitable for research and analytical applications. Our products undergo rigorous quality testing, including chromatographic purity analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific batch results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.