Description

1,2,3,4-Tetrakis(trifluoromethyl)-1-cyclobutene is a highly fluorinated, specialized organic compound characterized by its unique cyclobutene ring structure densely substituted with trifluoromethyl groups. This molecular architecture imparts exceptional chemical stability, lipophilicity, and electronic properties, making it a valuable building block for advanced materials and fine chemical synthesis. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel compounds with enhanced performance characteristics.

Application

• Advanced Pharmaceutical Intermediates: Serves as a key fluorinated synthon for introducing multiple CF3 groups into drug candidates, potentially improving metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides where the fluorinated moiety can enhance biological activity and environmental persistence profiles.
• Specialty Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing high-performance fluoropolymers with superior chemical resistance, low surface energy, and unique optical/electronic properties.
• Liquid Crystal & Electronic Materials: Employed in the design of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices due to its influence on dielectric constant and molecular ordering.
• Catalysis & Ligand Development: Utilized as a precursor for creating novel fluorinated ligands that can modify the activity and selectivity of metal catalysts in organic transformations.
• High-Energy Materials & Propellants: Investigated for applications in energetic material formulations where the high density of fluorine and carbon can contribute to performance characteristics.

Basic Information

Item	Detail
Product Name	1,2,3,4-Tetrakis(trifluoromethyl)-1-cyclobutene
CAS No.	74367-21-8
Molecular Formula	C10F12
Molecular Weight	372.09 g/mol
Synonyms	Perfluoro(1,2,3,4-tetrakis(trifluoromethyl)cyclobutene); 1-Cyclobutene, 1,2,3,4-tetrakis(trifluoromethyl)-; Octafluoro-2-(trifluoromethyl)-3-[(trifluoromethyl)ethynyl]-2-butene; 1,2,3,4-Tetrakis(trifluoromethyl)cyclobut-1-ene; FC-75 (related trade name context); Perfluorinated cyclobutene derivative; Hexadecafluorotetrakis(trifluoromethyl)cyclobutene
EINECS	Contact for details

Quality Control

Every batch of 1,2,3,4-Tetrakis(trifluoromethyl)-1-cyclobutene is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for research and industrial use. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with precise customer specifications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to strong bases and certain reactive conditions; ensure the storage area is separate from incompatible materials. Keep container tightly sealed when not in use to prevent contamination and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0% (Area %)
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Non-volatile Residue	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.