Description

2-Azetidinebutanoic Acid, A-Diazo-3-(1-Hydroxyethyl)-B,4-Dioxo-, (4-Nitrophenyl)Methyl Ester, [2R-[2A,3B(R*)]]- is a specialized chiral azetidine derivative featuring a diazo and dioxo functional group, making it a valuable synthetic intermediate. This compound is significant for its role in advanced organic synthesis, particularly in the construction of complex, biologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic effects.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fine chemicals.
• Academic Research: A valuable reagent for universities and research institutes focusing on novel heterocyclic chemistry and asymmetric synthesis methodologies.

Basic Information

Product Name	2-Azetidinebutanoic Acid, A-Diazo-3-(1-Hydroxyethyl)-B,4-Dioxo-, (4-Nitrophenyl)Methyl Ester, [2R-[2A,3B(R*)]]-
CAS No.	74288-39-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(4-Nitrophenyl)methyl (2R,3R)-2-diazo-3-[(1R)-1-hydroxyethyl]-4-oxoazetidine-2-butanoate; [2R-[2α,3β(R*)]]-α-Diazo-3-(1-hydroxyethyl)-β,4-dioxo-2-azetidinebutanoic Acid 4-Nitrobenzyl Ester; 4-Nitrobenzyl (2R,3R)-2-diazo-3-[(1R)-1-hydroxyethyl]-4-oxo-1-azetidinebutanoate; Azetidine-2-butanoic Acid Derivative; Chiral Diazo Azetidinone Ester; 74288-39-4
EINECS	Contact for details

Quality Control

Our 2-Azetidinebutanoic Acid derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as chiral purity, assay, and impurity profile are available upon request. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, storage at temperatures between 2°C and 8°C (refrigerated) is recommended. Keep the container tightly sealed under an inert atmosphere if specified. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.