Description

Diethyl (2R,3R)-(-)-2,3-Epoxysuccinate is a high-value chiral epoxide building block essential for asymmetric synthesis. This enantiomerically pure compound serves as a critical intermediate in the production of complex, biologically active molecules, enabling precise stereochemical control. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis: Employed as a starting material or ligand precursor in the development of chiral catalysts for stereoselective reactions.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances with defined stereocenters.
• Academic & Industrial Research: A valuable tool in organic chemistry research for method development and exploring new synthetic pathways.

Basic Information

Product Name	Diethyl (2R,3R)-(-)-2,3-Epoxysuccinate
CAS No.	74243-85-9
Molecular Formula	C8H12O5
Molecular Weight	188.18 g/mol
Synonyms	(-)-Diethyl L-Tartrate Epoxide; Diethyl (2R,3R)-2,3-Epoxybutanedioate; (2R,3R)-(-)-Diethyl Oxirane-2,3-dicarboxylate; L-(-)-Diethyl Tartrate Epoxide; Diethyl (2R,3R)-(-)-Epoxysuccinate; (2R,3R)-Diethyl 2,3-Epoxysuccinate; Diethyl (2R,3R)-2,3-Epoxysuccinate; (R,R)-Diethyl Epoxysuccinate
EINECS	Contact for details

Quality Control

Our Diethyl (2R,3R)-(-)-2,3-Epoxysuccinate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	-30° to -34° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.