Description

2-(Cyclohexylidenemethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a pinacol boronate ester, essential for modern synthetic chemistry. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is critical for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the cyclohexylidene moiety into complex molecular frameworks.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research: An indispensable tool in academic and industrial R&D for constructing complex organic molecules and exploring new synthetic pathways.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Used in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	2-(Cyclohexylidenemethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	74213-49-3
Molecular Formula	C₁₃H₂₃BO₂
Molecular Weight	222.13 g/mol
Synonyms	Cyclohexylidenemethylboronic Acid Pinacol Ester; (Cyclohexylidenemethyl)boronic Acid Pinacol Ester; trans-2-(Cyclohexylidenemethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclohexylmethyleneboronic Acid Pinacol Ester; B-(Cyclohexylidenemethyl)boronic Acid Pinacol Ester; 2-[(Cyclohexylidene)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclohexylidene Methyl Pinacol Boronate
EINECS	Contact for details

Quality Control

Our production of 2-(Cyclohexylidenemethyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing assay and impurity profiles to meet the exacting standards of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.