Description

(Z)-4,4,5,5-Tetramethyl-2-Styryl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation, particularly in Suzuki-Miyaura cross-coupling reactions, which are fundamental to pharmaceutical and materials science research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and styryl motifs prevalent in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific styryl-boronate structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing conjugated organic semiconductors and emissive layer materials.
• Polymer & Material Science: Employed to create functionalized monomers for advanced polymers with tailored optical or electronic properties.
• Cross-Coupling Methodology Development: A standard substrate in academic and industrial laboratories for optimizing new catalytic systems and reaction conditions.
• Ligand & Catalyst Design: Used to introduce boronate handles into complex molecules for further functionalization or as part of catalyst frameworks.

Basic Information

Product Name	(Z)-4,4,5,5-Tetramethyl-2-Styryl-1,3,2-Dioxaborolane
CAS No.	74213-48-2
Molecular Formula	C16H23BO2
Molecular Weight	258.17 g/mol
Synonyms	trans-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)styrene; (Z)-2-Styryl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-4,4,5,5-Tetramethyl-2-(2-phenylethenyl)-1,3,2-dioxaborolane; (Z)-2-(2-Phenylethenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Styrylboronic Acid Pinacol Ester (Z-isomer); (Z)-StyrylBpin; (Z)-Vinylphenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Every batch of (Z)-4,4,5,5-Tetramethyl-2-Styryl-1,3,2-Dioxaborolane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity, identity, and lot-to-lot consistency. Our products are developed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profile is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.