Description

1-(2-Methoxyphenyl)Cyclobutane-1-Carboxylic Acid is a specialized organic building block featuring a cyclobutane ring substituted with a carboxylic acid and a 2-methoxyphenyl group. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection. The compound, with CAS number 74205-38-2, is supplied to meet the stringent purity requirements of modern organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its rigid cyclobutane core for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers with tailored thermal or mechanical properties.
• Ligand Synthesis: The carboxylic acid and aromatic ether functionalities make it a useful starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function or cellular processes.
• Academic & Contract Research: Essential for fundamental organic chemistry research and for contract research organizations (CROs) supporting drug discovery programs.

Basic Information

Product Name	1-(2-Methoxyphenyl)Cyclobutane-1-Carboxylic Acid
CAS No.	74205-38-2
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	2-Methoxy-α-cyclobutanebenzeneacetic acid; 1-(2-Methoxyphenyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(2-methoxyphenyl)-; o-Methoxyphenylcyclobutanecarboxylic acid; 1-Cyclobutyl-2-methoxybenzoic acid; (2-Methoxyphenyl)cyclobutanecarboxylic acid; 74205-38-2; 1-(2-Methoxyphenyl)-1-cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxyphenyl)Cyclobutane-1-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.