Description

(1R)-1,2,3,4,4A,5,6,8Aβ-Octahydro-4Aα,8-Dimethyl-2α-Isopropylnaphthalen-1-Ol CAS NO 74144-55-1 is a high-purity, stereochemically defined decalin derivative, valued for its role as a versatile chiral intermediate and building block in advanced organic synthesis. Its rigid, polycyclic structure and defined stereocenters make it crucial for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and fragrances.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold for the synthesis of novel therapeutic agents, particularly in steroid-mimetic and terpenoid-based drug discovery.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides with enhanced stereospecificity and biological activity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthetic musk compounds and other complex odorants due to its stable, woody decalin backbone.
• Asymmetric Catalysis Ligand Synthesis: Provides a structurally rigid framework for developing novel chiral ligands and organocatalysts.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal and mechanical properties derived from its bicyclic structure.
• Reference Standard: Employed as an analytical standard in chromatography (GC, HPLC) for quality control and method development in related chemical processes.

Basic Information

Product Name	(1R)-1,2,3,4,4A,5,6,8Aβ-Octahydro-4Aα,8-Dimethyl-2α-Isopropylnaphthalen-1-Ol
CAS No.	74144-55-1
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	(1R,2S,4aR,8aR)-1,2,3,4,4a,5,6,8a-Octahydro-4a,8-dimethyl-2-(1-methylethyl)-1-naphthalenol; (1R)-1,2,3,4,4a,5,6,8a-Octahydro-4a,8-dimethyl-2-(1-methylethyl)-1-naphthalenol; Decahydro-4a,8-dimethyl-2-(1-methylethyl)-1-naphthalenol (stereoisomer); Chiral Decalin Alcohol; 2-Isopropyl-4a,8-dimethyldecalin-1-ol
EINECS	Contact for details

Quality Control

Our (1R)-1,2,3,4,4A,5,6,8Aβ-Octahydro-4Aα,8-Dimethyl-2α-Isopropylnaphthalen-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC and GC, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.