Description

Phenethylamine, α-Ethyl-α-Methyl-m-Trifluoromethyl- is a specialized trifluoromethylated phenethylamine derivative, a high-value building block prized for its unique structural motif that combines a phenethylamine core with strategic alkyl and fluorine substitutions. This compound is critical for advanced research and development, particularly in the synthesis of novel bioactive molecules where the trifluoromethyl group is leveraged to modulate lipophilicity, metabolic stability, and binding affinity. It is primarily sought by pharmaceutical research organizations, agrochemical developers, and specialty chemical manufacturers engaged in creating next-generation compounds for therapeutic and agrochemical applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets, antidepressants, and neuroactive compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, benefiting from the steric and electronic influence of the substituents.
• Material Science Precursor: Potential building block for advanced organic materials, such as liquid crystals or fluorinated polymers, where its aromatic and fluorinated structure can impart specific properties.
• Biochemical Tool Compound: Utilized in life science research as a probe or reference standard to study enzyme interactions, receptor binding, or metabolic pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	Phenethylamine, α-Ethyl-α-Methyl-m-Trifluoromethyl-
CAS No.	74051-19-7
Molecular Formula	C12H16F3N
Molecular Weight	231.26 g/mol
Synonyms	α-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine; 1-[3-(Trifluoromethyl)phenyl]-2-methylbutan-1-amine; 2-Methyl-1-[3-(trifluoromethyl)phenyl]butan-1-amine; m-Trifluoromethyl-α-ethyl-α-methylphenethylamine; Benzenepropanamine, α-ethyl-α-methyl-3-(trifluoromethyl)-; 3'-(Trifluoromethyl)-α-ethyl-α-methylphenethylamine
EINECS	Contact for details

Quality Control

Our Phenethylamine, α-Ethyl-α-Methyl-m-Trifluoromethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.