Description

6-(3-Nitrophenyl)-4-Oxo-5-Hexenoic Acid is a specialized organic intermediate featuring a nitro-substituted phenyl ring conjugated with an α,β-unsaturated ketone and a carboxylic acid functional group. This unique structure makes it a valuable synthon for constructing more complex molecules in pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for use in targeted synthesis programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a nitroarene or cinnamic acid derivative scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the nitro and keto-acid functionalities can be modified for bioactivity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, or liquid crystals due to its polymerizable double bond and aromaticity.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for studying Michael addition reactions, reduction of nitro groups, and other transformations central to synthetic chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments, where the nitro group can influence color and lightfastness properties.

Basic Information

Product Name	6-(3-Nitrophenyl)-4-Oxo-5-Hexenoic Acid
CAS No.	74038-57-6
Molecular Formula	C12H11NO5
Molecular Weight	249.22 g/mol
Synonyms	4-Oxo-6-(3-nitrophenyl)-5-hexenoic acid; 5-Hexenoic acid, 6-(3-nitrophenyl)-4-oxo-; (E)-6-(3-Nitrophenyl)-4-oxohex-5-enoic acid; 3-Nitrocinnamoylacetic acid; β-(3-Nitrobenzoyl)acrylic acid; 4-Oxo-6-(m-nitrophenyl)-5-hexenoic acid
EINECS	Contact for details

Quality Control

Our production of 6-(3-Nitrophenyl)-4-Oxo-5-Hexenoic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.