Description

Rokitamycin CAS NO 74014-51-0 is a 16-membered macrolide antibiotic derived from *Streptomyces kitasatoensis*. This semi-synthetic compound is valued for its potent antibacterial activity against a range of Gram-positive and some Gram-negative pathogens, including macrolide-resistant strains. It is primarily utilized in the pharmaceutical industry for the research, development, and production of advanced antibacterial formulations.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of oral antibacterial medications.
• Veterinary Medicine: Used in formulations for treating bacterial infections in livestock and companion animals.
• Clinical Research: Serves as a reference standard and investigational compound in antimicrobial resistance studies.
• Microbiological Studies: Employed in laboratory settings to study bacterial growth inhibition and mechanism of action.
• Drug Intermediate: Acts as a key starting material or intermediate in the synthesis of more complex antibiotic derivatives.

Basic Information

Product Name	Rokitamycin
CAS No.	74014-51-0
Molecular Formula	C42H69NO15
Molecular Weight	828.0 g/mol
Synonyms	Rokitamycin; TMS-19-Q; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]methyl}-14-ethyl-12,13-dihydroxy-4-{[(2R,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; Antibiotic TMS-19-Q
EINECS	Contact for details

Quality Control

Our Rokitamycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and tests for residual solvents and related substances, to ensure it meets high-grade pharmaceutical standards. A Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.