Description

2-(4-Chlorophenyl)-1,3-Dioxolane-4-Methanol is a versatile organic intermediate characterized by its dioxolane-protected aldehyde functionality and chlorinated aromatic ring. This compound matters for its role as a key chiral building block in the synthesis of complex molecules, offering chemists a protected formyl equivalent for selective transformations. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides, where the chlorophenyl moiety contributes to biological activity.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Process Chemistry: A valuable tool for methodological studies in organic synthesis and for scaling up novel synthetic routes in process development.

Basic Information

Product Name	2-(4-Chlorophenyl)-1,3-Dioxolane-4-Methanol
CAS No.	73987-13-0
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	4-(Chlorophenyl)-2-(hydroxymethyl)-1,3-dioxolane; (4-Chlorophenyl)-1,3-dioxolane-4-methanol; 2-(p-Chlorophenyl)-1,3-dioxolane-4-methanol; 4-(Hydroxymethyl)-2-(4-chlorophenyl)-1,3-dioxolane; 1,3-Dioxolane-4-methanol, 2-(4-chlorophenyl)-; p-Chlorophenyl dioxolane methanol; 4-Chlorobenzaldehyde ethylene acetal methanol
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-1,3-Dioxolane-4-Methanol is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.