Description

S-(o-Ethyl Phenylphosphonothionyl)Glutathione is a specialized organophosphorus-glutathione conjugate, a key intermediate in biochemical research and advanced synthesis. This compound is of significant interest for studying detoxification pathways and enzyme interactions involving glutathione S-transferases. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, agrochemical research, and toxicology studies to investigate metabolic processes and develop novel bioactive molecules.

Application

• Biochemical Research: Critical intermediate for studying glutathione S-transferase (GST) enzyme activity and metabolic conjugation pathways.
• Metabolite Standard: Used as a reference standard in analytical chemistry (LC-MS, HPLC) for the identification and quantification of organophosphorus compound metabolites.
• Toxicology & Mechanistic Studies: Employed to investigate the detoxification mechanisms and bioactivation of phosphonothionate pesticides and related chemicals.
• Pharmaceutical Development: Serves as a building block or probe in the discovery of drugs targeting oxidative stress and cellular defense systems.
• Agrochemical Research: Used in the development and safety profiling of next-generation insecticides and herbicides to understand their environmental fate and metabolism.
• Academic Research: A valuable tool in university and institutional labs for fundamental research in bioorganic chemistry and molecular toxicology.

Basic Information

Product Name	S-(o-Ethyl Phenylphosphonothionyl)Glutathione
CAS No.	73962-44-4
Molecular Formula	C18H28N3O7PS2
Molecular Weight	493.53 g/mol
Synonyms	S-(2-Ethoxy-phenylphosphinothioyl)glutathione; Glutathione S-(o-ethyl phenylphosphonothioate); o-Ethyl phenylphosphonothioic acid S-(glutathion-1-yl) ester; Phenylphosphonothioic acid, o-ethyl-, S-ester with glutathione; GST Conjugate of o-Ethyl phenylphosphonothionate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our S-(o-Ethyl Phenylphosphonothionyl)Glutathione is produced under stringent conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.