Description

4-[(Difluoromethyl)Sulfanyl]Benzaldehyde is a specialized aromatic aldehyde building block featuring a difluoromethylthio (-SCF2H) substituent. This unique molecular architecture, combining an aldehyde group with a fluorinated sulfur moiety, makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients. It is primarily sought by research chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel compounds with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors where the difluoromethylthio group can modulate potency, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, where the introduction of fluorine atoms is known to improve biological activity, environmental stability, and uptake in target organisms.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced organic electronic materials, contributing to the molecular core of compounds used in display technologies and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligands with tailored electronic properties for transition metal complexes.
• Polymer & Resin Modifier: Can be incorporated into polymer backbones or as a cross-linking agent to impart specific characteristics like altered refractive index or chemical resistance to advanced polymeric materials.

Basic Information

Product Name	4-[(Difluoromethyl)Sulfanyl]Benzaldehyde
CAS No.	73960-05-1
Molecular Formula	C8H6F2OS
Molecular Weight	188.20 g/mol
Synonyms	4-(Difluoromethylthio)benzaldehyde; p-(Difluoromethylthio)benzaldehyde; Benzaldehyde, 4-[(difluoromethyl)thio]-; 4-SCF2H-Benzaldehyde; 4-(Difluoromethylsulfanyl)benzaldehyde; 4-(Difluoromethylmercapto)benzaldehyde; 73960-05-1; 4-Difluoromethylthiobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-[(Difluoromethyl)Sulfanyl]Benzaldehyde is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.