Description

Diethyl (2S,3S)-(+)-2,3-Epoxysuccinate is a high-purity chiral epoxide derivative of diethyl tartrate, serving as a critical chiral building block and synthetic intermediate. Its enantiopure nature and reactive epoxide functionality make it indispensable for the stereoselective synthesis of complex molecules. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, including protease inhibitors, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for efficacy and environmental safety.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for stereoselective transformations.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, fragrances, and advanced polymers requiring defined stereochemistry.
• Academic & R&D: A valuable reagent in organic chemistry research for methodological development and the study of epoxide ring-opening reactions.

Basic Information

Product Name	Diethyl (2S,3S)-(+)-2,3-Epoxysuccinate
CAS No.	73890-18-3
Molecular Formula	C8H12O5
Molecular Weight	188.18 g/mol
Synonyms	(+)-Diethyl L-tartrate epoxide; Diethyl (2S,3S)-(-)-2,3-epoxysuccinate; (2S,3S)-(-)-2,3-Epoxysuccinic acid diethyl ester; Diethyl (2S,3S)-2,3-epoxybutanedioate; L-(+)-2,3-Epoxysuccinic acid diethyl ester; Diethyl L-2,3-epoxysuccinate; (2S,3S)-(+)-2,3-Epoxybutanedioic acid diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl (2S,3S)-(+)-2,3-Epoxysuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]20/D	+30° to +35° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.