Description

1-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propylamine is a specialized aromatic amine derivative featuring a trifluoromethylphenyl group, which imparts unique physicochemical properties. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. Key industries that utilize this intermediate include pharmaceutical research, agrochemical manufacturing, and specialty chemical production, where its structural motif is critical for creating molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Used as a reactive handle for bioconjugation and probe development in biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific R&D projects.

Basic Information

Item	Detail
Product Name	1-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	73839-94-8
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]-1-methylpropylamine; 1-Methyl-3-[3-(trifluoromethyl)phenyl]propan-1-amine; α-Methyl-3-(trifluoromethyl)benzenepropanamine; 3-(3-Trifluoromethylphenyl)-1-methylpropylamine; N-Methyl-3-(3-trifluoromethylphenyl)propylamine; 73839-94-8; Benzenepropanamine, α-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propylamine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support compliance with REACH, FDA guidelines for drug intermediates, and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This amine is a strong base and should be kept away from strong acids and oxidizing agents. Keep container tightly sealed when not in use to minimize exposure to moisture and atmospheric carbon dioxide.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.